diff --git a/src/PhpSpreadsheet/Reader/Xlsx/ConditionalStyles.php b/src/PhpSpreadsheet/Reader/Xlsx/ConditionalStyles.php
index b3de5d1c..722b7795 100644
--- a/src/PhpSpreadsheet/Reader/Xlsx/ConditionalStyles.php
+++ b/src/PhpSpreadsheet/Reader/Xlsx/ConditionalStyles.php
@@ -36,6 +36,8 @@ class ConditionalStyles
                 if (((string) $cfRule['type'] == Conditional::CONDITION_NONE
                     || (string) $cfRule['type'] == Conditional::CONDITION_CELLIS
                     || (string) $cfRule['type'] == Conditional::CONDITION_CONTAINSTEXT
+                    || (string) $cfRule['type'] == Conditional::CONDITION_CONTAINSBLANKS
+                    || (string) $cfRule['type'] == Conditional::CONDITION_NOTCONTAINSBLANKS
                     || (string) $cfRule['type'] == Conditional::CONDITION_EXPRESSION)
                     && isset($this->dxfs[(int) ($cfRule['dxfId'])])) {
                     $conditionals[(string) $conditional['sqref']][(int) ($cfRule['priority'])] = $cfRule;
diff --git a/src/PhpSpreadsheet/Style/Conditional.php b/src/PhpSpreadsheet/Style/Conditional.php
index 91a000db..48375937 100644
--- a/src/PhpSpreadsheet/Style/Conditional.php
+++ b/src/PhpSpreadsheet/Style/Conditional.php
@@ -12,6 +12,7 @@ class Conditional implements IComparable
     const CONDITION_CONTAINSTEXT = 'containsText';
     const CONDITION_EXPRESSION = 'expression';
     const CONDITION_CONTAINSBLANKS = 'containsBlanks';
+    const CONDITION_NOTCONTAINSBLANKS = 'notContainsBlanks';
 
     // Operator types
     const OPERATOR_NONE = '';
diff --git a/src/PhpSpreadsheet/Writer/Xlsx/Worksheet.php b/src/PhpSpreadsheet/Writer/Xlsx/Worksheet.php
index f148b7c3..bf811bdc 100644
--- a/src/PhpSpreadsheet/Writer/Xlsx/Worksheet.php
+++ b/src/PhpSpreadsheet/Writer/Xlsx/Worksheet.php
@@ -527,6 +527,9 @@ class Worksheet extends WriterPart
                     } elseif ($conditional->getConditionType() == Conditional::CONDITION_CONTAINSBLANKS) {
                         // formula copied from ms xlsx xml source file
                         $objWriter->writeElement('formula', 'LEN(TRIM(' . $cellCoordinate . '))=0');
+                    } elseif ($conditional->getConditionType() == Conditional::CONDITION_NOTCONTAINSBLANKS) {
+                        // formula copied from ms xlsx xml source file
+                        $objWriter->writeElement('formula', 'LEN(TRIM(' . $cellCoordinate . '))>0');
                     }
 
                     $objWriter->endElement();
diff --git a/tests/PhpSpreadsheetTests/Reader/Xlsx2Test.php b/tests/PhpSpreadsheetTests/Reader/Xlsx2Test.php
new file mode 100644
index 00000000..0544d74a
--- /dev/null
+++ b/tests/PhpSpreadsheetTests/Reader/Xlsx2Test.php
@@ -0,0 +1,123 @@
+<?php
+
+namespace PhpOffice\PhpSpreadsheetTests\Reader;
+
+use PhpOffice\PhpSpreadsheet\IOFactory;
+use PhpOffice\PhpSpreadsheet\Shared\File;
+use PhpOffice\PhpSpreadsheet\Style\Color;
+use PhpOffice\PhpSpreadsheet\Style\Conditional;
+use PhpOffice\PhpSpreadsheet\Style\Fill;
+use PHPUnit\Framework\TestCase;
+
+class Xlsx2Test extends TestCase
+{
+    public function tearDown()
+    {
+        $outfile = tempnam(File::sysGetTempDir(), 'phpspreadsheet-test');
+        if (file_exists($outfile)) {
+            unlink($outfile);
+        }
+    }
+
+    public function testLoadXlsxConditionalFormatting2()
+    {
+        // Make sure Conditionals are read correctly from existing file
+        $filename = './data/Reader/XLSX/conditionalFormatting2Test.xlsx';
+        $reader = IOFactory::createReader('Xlsx');
+        $spreadsheet = $reader->load($filename);
+        $worksheet = $spreadsheet->getActiveSheet();
+
+        $conditionalStyle = $worksheet->getConditionalStyles('A2:A8');
+        self::assertNotEmpty($conditionalStyle);
+        $conditionalRule = $conditionalStyle[0];
+        $conditions = $conditionalRule->getConditions();
+        self::assertNotEmpty($conditions);
+        self::assertEquals(Conditional::CONDITION_NOTCONTAINSBLANKS, $conditionalRule->getConditionType());
+        self::assertEquals('LEN(TRIM(A2))>0', $conditions[0]);
+
+        $conditionalStyle = $worksheet->getConditionalStyles('B2:B8');
+        self::assertNotEmpty($conditionalStyle);
+        $conditionalRule = $conditionalStyle[0];
+        $conditions = $conditionalRule->getConditions();
+        self::assertNotEmpty($conditions);
+        self::assertEquals(Conditional::CONDITION_CONTAINSBLANKS, $conditionalRule->getConditionType());
+        self::assertEquals('LEN(TRIM(B2))=0', $conditions[0]);
+
+        $conditionalStyle = $worksheet->getConditionalStyles('C2:C8');
+        self::assertNotEmpty($conditionalStyle);
+        $conditionalRule = $conditionalStyle[0];
+        $conditions = $conditionalRule->getConditions();
+        self::assertNotEmpty($conditions);
+        self::assertEquals(Conditional::CONDITION_CELLIS, $conditionalRule->getConditionType());
+        self::assertEquals(Conditional::OPERATOR_GREATERTHAN, $conditionalRule->getOperatorType());
+        self::assertEquals('5', $conditions[0]);
+    }
+
+    public function testReloadXlsxConditionalFormatting2()
+    {
+        // Make sure conditionals from existing file are maintained across save
+        $filename = './data/Reader/XLSX/conditionalFormatting2Test.xlsx';
+        $outfile = tempnam(File::sysGetTempDir(), 'phpspreadsheet-test');
+        $reader = IOFactory::createReader('Xlsx');
+        $spreadshee1 = $reader->load($filename);
+        $writer = IOFactory::createWriter($spreadshee1, 'Xlsx');
+        $writer->save($outfile);
+        $spreadsheet = $reader->load($outfile);
+        $worksheet = $spreadsheet->getActiveSheet();
+
+        $conditionalStyle = $worksheet->getConditionalStyles('A2:A8');
+        self::assertNotEmpty($conditionalStyle);
+        $conditionalRule = $conditionalStyle[0];
+        $conditions = $conditionalRule->getConditions();
+        self::assertNotEmpty($conditions);
+        self::assertEquals(Conditional::CONDITION_NOTCONTAINSBLANKS, $conditionalRule->getConditionType());
+        self::assertEquals('LEN(TRIM(A2:A8))>0', $conditions[0]);
+
+        $conditionalStyle = $worksheet->getConditionalStyles('B2:B8');
+        self::assertNotEmpty($conditionalStyle);
+        $conditionalRule = $conditionalStyle[0];
+        $conditions = $conditionalRule->getConditions();
+        self::assertNotEmpty($conditions);
+        self::assertEquals(Conditional::CONDITION_CONTAINSBLANKS, $conditionalRule->getConditionType());
+        self::assertEquals('LEN(TRIM(B2:B8))=0', $conditions[0]);
+
+        $conditionalStyle = $worksheet->getConditionalStyles('C2:C8');
+        self::assertNotEmpty($conditionalStyle);
+        $conditionalRule = $conditionalStyle[0];
+        $conditions = $conditionalRule->getConditions();
+        self::assertNotEmpty($conditions);
+        self::assertEquals(Conditional::CONDITION_CELLIS, $conditionalRule->getConditionType());
+        self::assertEquals(Conditional::OPERATOR_GREATERTHAN, $conditionalRule->getOperatorType());
+        self::assertEquals('5', $conditions[0]);
+    }
+
+    public function testNewXlsxConditionalFormatting2()
+    {
+        // Make sure blanks/non-blanks added by PhpSpreadsheet are handled correctly
+        $outfile = tempnam(File::sysGetTempDir(), 'phpspreadsheet-test');
+        $spreadshee1 = new \PhpOffice\PhpSpreadsheet\Spreadsheet();
+        $sheet = $spreadshee1->getActiveSheet();
+        $sheet->setCellValue('A2', 'a2');
+        $sheet->setCellValue('A4', 'a4');
+        $sheet->setCellValue('A6', 'a6');
+        $cond1 = new Conditional();
+        $cond1->setConditionType(Conditional::CONDITION_CONTAINSBLANKS);
+        $cond1->getStyle()->getFill()->setFillType(Fill::FILL_SOLID);
+        $cond1->getStyle()->getFill()->getEndColor()->setARGB(Color::COLOR_RED);
+        $cond = [$cond1];
+        $sheet->getStyle('A1:A6')->setConditionalStyles($cond);
+        $writer = IOFactory::createWriter($spreadshee1, 'Xlsx');
+        $writer->save($outfile);
+        $reader = IOFactory::createReader('Xlsx');
+        $spreadsheet = $reader->load($outfile);
+        $worksheet = $spreadsheet->getActiveSheet();
+
+        $conditionalStyle = $worksheet->getConditionalStyles('A1:A6');
+        self::assertNotEmpty($conditionalStyle);
+        $conditionalRule = $conditionalStyle[0];
+        $conditions = $conditionalRule->getConditions();
+        self::assertNotEmpty($conditions);
+        self::assertEquals(Conditional::CONDITION_CONTAINSBLANKS, $conditionalRule->getConditionType());
+        self::assertEquals('LEN(TRIM(A1:A6))=0', $conditions[0]);
+    }
+}
diff --git a/tests/data/Reader/XLSX/conditionalFormatting2Test.xlsx b/tests/data/Reader/XLSX/conditionalFormatting2Test.xlsx
new file mode 100644
index 00000000..cf2fa87e
Binary files /dev/null and b/tests/data/Reader/XLSX/conditionalFormatting2Test.xlsx differ